In the new work, Shigeru Tajima, of the Japanese National Institute of Infectious Disease, and colleagues compared the PRVABC59 American subtype, the ZIKV/Hu/Chiba/S36/2016 (ChibaS36) Pacific subtype and the ZIKV/Hu/NIID123/2016 (NIID123) Southeast Asian subtype. They examined the growth rates both in vitro and in mice, and observed the viral loads and levels of testis damage in the infected mice. The PRVABC59 and ChibaS36 strains had significantly higher growth ability than NIID123 in multiple types of isolated cells, with the American strain having the highest growth potential. Moreover, two weeks post-infection, the amount of infectious particles and viral RNA in the genital tracts of male mice was lowest in those animals infected with the NIID123 strain. At 6 weeks post-infection, there was more testis damage in the mice infected with the American PRVABC59 stain.
"These results raise the possibility that ZIKV have acquired elevated proliferative capacity and pathogenicity during the process of the virus spreading from Southeast Asia to the Americas through the Pacific Islands," the researchers say.
DNA Repair. DNA is more than just strands of cell; it is like a computer that directs and repairs your cell. If we manage to repair it or give the DNA the ability to do so on its own then we have more chances of surviving longer than we should. For example, cancer is the breakdown of DNA’s capacity to mend itself, so the key is in understanding how it works and maybe jumpstart it in order for it to repair itself. For simpler understanding, DNA is just like any machine, with regular tune-ups and oiling, it works just as fine. Also once the understanding of its working is there, we can enhance it as well. Controlled mutation may even give us super powers and Professor X will just be another bald guy in a wheel chair.