Now, researchers comparing American, Pacific and Southeast Asian subtypes of the virus in PLOS Neglected Tropical Diseases have concluded that the American-subtype strain has the highest ability to grow both in vitro and in vivo.
The synthetic and fully resorbable TIGR Matrix surgical mesh by Novus Scientific is currently being investigated by researchers in the Erasmus University Medical Center in Rotterdam, the Netherlands.
Yong-Su Jin, a University of Illinois professor of food science and human nutrition, led the research team that engineered the yeast strain, which produces tagatose in much larger quantities than traditional enzymatic manufacturing techniques and could help make tagatose a cost-effective alternative to sugar or high-fructose corn syrup.
The study found that petting zoos provide a reservoir for a diverse range of ESBL/AmpC-E species, and are a potential source for shedding these highly virulent pathogens that may be transmitted to humans -- mostly children -- that occasionally visit these facilities.
"The gene cluster in the fungus is unique -- through a simple genetic deletion, we have engineered a strain of the fungus that only produces high concentrations of the desired antibiotic," explained Abe. Professor Kiyoshi Kita, who retired from the University of Tokyo in 2016, dedicated a large portion of his career to understanding and curing African sleeping sickness.
Molecular biologists from the University of Groningen and their colleagues in Switzerland and Germany have now developed a pipeline to create and screen large numbers of new lantibiotic peptides. When the beads were incubated, the producer strain formed a single colony inside, secreting lantibiotics.
"After being vaccinated with a new strain of flu, our immune systems appear to be expanding and boosting antibodies generated by previous exposures to earlier flu viruses, whether by infection or vaccination," said George Georgiou, a professor of biomedical and chemical engineering and molecular biosciences, a leader in the field of therapeutics and immune responses and co-author of the study.
In an earlier work, the Boone and Andrews labs, in collaboration with Fink's group, established that mutations in 57 genes, about one percent of all yeast genes, have different outcomes between SC and Sigma, causing cell death in either one or the other strain, but not both.
Researchers at EPFL's Soft Transducers Laboratory and at the Department of Physiology of the University of Bern (Group Rohr) have developed an experimental device that lets scientists subject bioengineered heart tissue to highly dynamic strain cycles and measure its electrophysiological response.
The search engine, described in a paper published in Nature Biotechnology, could enable researchers and public health agencies to use genome sequencing data to monitor the spread of antibiotic resistance genes.
Once the user has designed a 3D model using standard CAD tools and chosen an appropriate polymer material, Microlight3D's algorithms calculate the path that the laser will take to create the object.
Through the use of genomic sequencing, scientists at the Wellcome Sanger Institute and Institut Pasteur estimate the strain of cholera causing the current outbreak in Yemen -- the worst cholera outbreak in recorded history -- came from Eastern Africa and entered Yemen with the migration of people in and out of the region.
Researchers analysing soil from Ireland long thought to have medicinal properties have discovered that it contains a previously unknown strain of bacteria which is effective against four of the top six superbugs that are resistant to antibiotics, including MRSA.
Genetically diverse bacterial strains that cause urinary tract infections differ in their ability to trigger protective immune responses in mice, potentially explaining why these infections frequently recur in many patients, according to a study published December 13 in the open-access journal PLOS Pathogens by Thomas Hannan and Scott Hultgren of Washington University School of Medicine, and colleagues.
Using a multidisciplinary approach, an international team of researchers from several institutions, including Baylor College of Medicine, reveals that complex interactions between sugars and the microbiome in human milk influence neonatal rotavirus infection.
In the journal mBio, published online on 13 November 2018, the team headed by Jessica Borgmann from the Chair of Microbial Biology describes a small RNA molecule that significantly affects antibiotic resistance as well as other processes inside the cell.