EMS provider receives £7m investment boost

EMS provider receives £7m investment boost

Chemigraphic, a provider of Electronic Manufacturing Services (EMS) to the fast-growth medical technology, defence and power systems sectors, has received £7 million investment from NVM Private Equity (NVM), from its Vintage III fund.

Are American Zika strains more virulent than Pacific and Asian strains?

Are American Zika strains more virulent than Pacific and Asian strains?

Now, researchers comparing American, Pacific and Southeast Asian subtypes of the virus in PLOS Neglected Tropical Diseases have concluded that the American-subtype strain has the highest ability to grow both in vitro and in vivo.

Bioinks to print therapeutics in 3D

Bioinks to print therapeutics in 3D

A team of researchers at Texas A&M University has developed an innovative way to print therapeutics in 3D for regenerative medicine.3D bioprinting is emerging as a promising method for rapidly fabricating cell-containing constructs for designing new, healthy, functional tissues.

The message that addiction is a disease makes substance users less likely to seek help

The message that addiction is a disease makes substance users less likely to seek help

Research finds that people with substance-use problems who read a message describing addiction as a disease are less likely to report wanting to engage in effective therapies, compared to those who read a message that addiction behaviors are subject to change.

Researchers document impact of coffee on bowels

Researchers document impact of coffee on bowels

Researchers examined changes to bacteria when fecal matter was exposed to coffee in a petri dish, and by studying the composition of feces after rats ingested differing concentrations of coffee over three days.

Clinical trial improves treatment of genetic rickets

Clinical trial improves treatment of genetic rickets

A new study shows a drug developed in conjunction with investigators at Indiana University School of Medicine to alleviate symptoms of a rare musculoskeletal condition is significantly more effective than conventional therapies.

Electric car switch on for health benefits

Electric car switch on for health benefits

Could the health benefits and reduced costs to healthcare systems be enough to justify subsidizing charging infrastructure to allow society to switch from the internal combustion engine to electric vehicles faster than current trends predict.

Device developer receives £23 million investment from growth equity fund

Device developer receives £23 million investment from growth equity fund

Medical device product developer Medtrade Products is to receive £23 million in investment from pan-European growth equity fund Tikehau Capital. Peter Cirenza, head of Tikehau Capital in the UK, said: “Tikehau Capital’s global presence and expertise will allow Medtrade to strengthen its position across its key markets.

How cancer drug inhibits DNA repair in cancer cells

How cancer drug inhibits DNA repair in cancer cells

"The use of cediranib to help stop cancer cells from repairing damage to their DNA could potentially be useful in a number of cancers that rely on the pathway the drug targets," said the study's lead investigator, Alanna Kaplan, a member of Glazer's team.

Enzyme PHLPP2 could be a viable drug target for treating prostate cancer

Enzyme PHLPP2 could be a viable drug target for treating prostate cancer

In a new study published in the Journal of Cell Biology, co-led by Dr. Trotman and Dr. Dawid Nowak, an assistant professor at Weill Cornell and a former postdoctoral fellow at the Trotman lab, researchers were able to halt the natural process of prostate cancer metastasis in mice by deleting the PHLPP2 enzyme.

Medtronic to acquire Titan Spine

Medtronic to acquire Titan Spine

We feel that surface-enhanced titanium implants combined with our comprehensive biologics portfolio can have a positive impact on patient outcomes in spinal procedures.". In bringing the two companies together, Medtronic will acquire Titan Spine's complete portfolio, which consists of a comprehensive line of titanium, surface-enhanced interbody fusion devices.

J&J’s Ethicon to acquire TachoSil surgical patch from Takeda for $400m

J&J’s Ethicon to acquire TachoSil surgical patch from Takeda for $400m

“These initial divestitures represent important steps in advancing the growth strategy Takeda.”. Takeda Pharmaceutical president and CEO Christophe Weber said: “These initial divestitures represent important steps in advancing the growth strategy Takeda outlined following our transformational acquisition of Shire earlier this year.

Pushing early beta-cell proliferation can halt autoimmune attack in type 1 diabetes model

Pushing early beta-cell proliferation can halt autoimmune attack in type 1 diabetes model

Kulkarni MD PhD, HMS Professor of Medicine and Co-Section Head of Islet and Regenerative Biology in the Joslin Diabetes Center, pushed the growth of beta cells while the animals were still young -- meaning organs of the immune system were still developing, and still susceptible to manipulation.

Researchers putting the brakes on lethal childhood cancer

Researchers putting the brakes on lethal childhood cancer

Accordingly, reintroduction of SNF5 into MRT cells also displaced MYC from chromatin (the complex of DNA, RNA and protein that form chromosomes), inhibiting pro-cancerous gene expression programs.

Removal of gene completely prevents development of aggressive pancreatic cancer in mice

Removal of gene completely prevents development of aggressive pancreatic cancer in mice

"We found that deleting the ATDC gene in pancreatic cells resulted in one of the most profound blocks of tumor formation ever observed in a well-known mice model engineered to develop pancreatic ductal adenocarcinoma, or PDA, which faithfully mimics the human disease," says corresponding author Diane Simeone, MD, director of the Pancreatic Cancer Center of NYU Langone Health's Perlmutter Cancer Center.

Tumor cells' drug addiction may be their downfall

Tumor cells' drug addiction may be their downfall

"Working with Simon Cook and his team at the Babraham Institute allowed us to apply their expert knowledge in cell signalling to better understand the mechanism of acquired resistance and excitingly, it has led to results that might change how MEK and other RAS-ERK pathway inhibitors, could be used for the treatment of cancer.".

Here's how cancer hijacks wound healing to create its own blood supply

Here's how cancer hijacks wound healing to create its own blood supply

The researchers have identified specific processes within endothelial cells -- the cells that line blood vessels -- that tumors use to build out their own blood supply.

How both mother and baby genes affect birth weight

How both mother and baby genes affect birth weight

Dr Rachel Freathy, a Sir Henry Dale Fellow at the University of Exeter Medical School, who was joint lead author on the study, said: "This is the first time we've really been able to unpick the effects of both mother and baby's genes on baby weight, which is an important health indicator.

Morning exercise can improve decision-making across the day in older adults

Morning exercise can improve decision-making across the day in older adults

Physical activity researcher, Michael Wheeler says the study highlights that uninterrupted sitting should be avoided to maintain optimal cognition across the day, and that moderate-intensity exercise such as a brisk walk should be encouraged for the daily maintenance of brain health.

Roche introduces Ventana HER2 Dual ISH assay

Roche introduces Ventana HER2 Dual ISH assay

Roche has launched the Ventana HER2 Dual ISH DNA Probe Cocktail, a companion diagnostic to detect which breast and gastric cancer patients are eligible for targeted therapy. Ventana HER2 Dual ISH DNA Probe Cocktail assay is intended to identify patients for targeted therapy with the company’s Herceptin (trastuzumab) medicine.

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