Now, researchers comparing American, Pacific and Southeast Asian subtypes of the virus in PLOS Neglected Tropical Diseases have concluded that the American-subtype strain has the highest ability to grow both in vitro and in vivo.
Paromomysin-based topical treatments were shown to be effective in curing cutaneous leishmaniasis (CL), according to a randomized, double blind study conducted in Panama and published with PLOS Neglected Tropical Diseases.
"The gene cluster in the fungus is unique -- through a simple genetic deletion, we have engineered a strain of the fungus that only produces high concentrations of the desired antibiotic," explained Abe. Professor Kiyoshi Kita, who retired from the University of Tokyo in 2016, dedicated a large portion of his career to understanding and curing African sleeping sickness.
A study published on March 28, 2019, in PLOS Neglected Tropical Diseases predicts that climate change and rising global temperatures will lead to both increased and new exposures to humans of diseases carried by mosquito vectors Aedes aegypti and Ae. The most extreme instances of transmission are predicted to occur at intermediate climate change scenarios.
Researchers reporting in PLOS Neglected Tropical Diseases investigated this claim using a 'vaccine probe' analysis of a completed cholera vaccine cluster randomized trial to support the sensitivity of conventional microbiological culture for cholera.
Researchers reporting in PLOS Neglected Tropical Diseases have now analyzed temporal and demographic patterns in gestational syphilis (GS) and mother-to-child-transmission (MTCT) of syphilis. In many cities, however, the number of MTCT cases was larger than the number of reported GS cases, suggesting a failure in the notification system.
Now, researchers reporting in PLOS Neglected Tropical Diseases have carried out an extensive social sciences evaluation of how populations in Cameroon interact with nonhuman primates, pointing toward behaviors that could put people at risk of infection with new diseases.
Now, researchers reporting in PLOS Neglected Tropical Diseases have found that an exam of just a patient's hands, feet and lower legs may have the potential to catch more than 90 percent of all scabies cases, regardless of severity.
Now, researchers reporting in PLOS Neglected Tropical Diseases have shown that schistosomiasis infections are associated with increased HIV onward transmission, HIV acquisition in HIV negative women with urogenital schistosomiasis, and progression to death in HIV positive women.
Now, researchers reporting in PLOS Neglected Tropical Diseases have showed that a natural flavonoid is effective at treating Leishmania amazonensis infections. amazonensis parasite cells, and then went on to test the effectiveness of the compound in treating mice with L.
A study in PLOS Neglected Tropical Diseases by Hannah Frank and colleagues at Stanford University, California suggests that humans play an important role in disease risk, infection patterns, and distribution of Bartonella, advancing current understanding of Bartonella's evolutionary history and how the bacteria may be transmitted between humans and other animal species.
A study published in PLOS Neglected Tropical Diseases, by Mirdad Kazanji, of the Centre International de Recherches Medicales de Franceville in Gabon, and the Institut Pasteur de la Guyane in French Guiana, suggests that 30 years after the first epidemiological survey of the seroprevalence of Human T-cell lymphotropic virus type 1 (HTLV-1) infections in Gabon, the country remains highly endemic, with a seroprevalence of 7.3%.
By collecting DNA from the guts of these bugs, researchers reporting in PLOS Neglected Tropical Diseases have described patterns in the behavior of the bugs, the strain of parasite, and the communities of microbes that interact with the parasite.
Researchers report this week in PLOS Neglected Tropical Diseases that new controls and frameworks are recommended to detect dengue and other infectious diseases and help prevent their spread during the summer games. "We specifically applied the FMEA framework to health preparedness for dengue infection for Tokyo 2020.